Roles and responsibilities
Janelle Sauvageau works as a Research Officer in the glyco-chemistry team in HHT. She synthesises and analyze charged glycans and develop syntheses for vaccines and immunomodulators. Her main project is the synthesis of phosphated heptoses as immunomodulators. She is the chair of the chemical safety committee where their safe disposal and inventory is the main goal of the committee.
Current research and/or projects
Janelle Sauvageau is an expert in carbohydrate synthesis and analysis. Her contribution is to apply this field to human health therapeutics.
Research and/or project statements
-Synthesis of charged carbohydrate to access their potential as immunomodulators
-Analysis of carbohydrates using ion exchange and electrochemical detection
-Synthesis of glycans for assessment as conjugate vaccines
-Chairing the chemical committee
Ph.D. Chemistry, Victoria University of Wellington (New Zealand) 2013
M.Sc. Chemistry, Université Laval, 2004
B.Sc. Chemistry, Université Laval, 2004
Work with students, organize talks
Adjunct Professor, INRS, Armand-Frappier
Instant Award, Certificate of Excellence (Ambassador, NRC)
Adekoya, I. A., Guo, C. X., Gray-Owen, S. D., D. Cox, A., Sauvageau, J. (2018) d-Glycero-β-d-manno-heptose 1-phosphate and d-glycero-β-d-manno-heptose 1,7-biphosphate are both innate immune agonists. J. Immunol., 201, 2385-2391.
Sauvageau, J., Bhasin, M., Guo, C.X., Gray-Owen, S.D., Oscarson, S., Guazzelli, L., Cox, A. (2017) Alternate synthesis to d-glycero-β-d-manno-heptose 1,7-biphosphate. Carbohydr. Res., 450, 38-43.
Yimei, J., McCluskie, M.J., Zhang, D., Monette, R., Iqbal, U., Moreno, M., Deschatelets, L., Sauvageau, J., Williams, D., Jakubek, Z.J., Krishnan, L. (2017) In vitro evaluation of archaeosome vehicles for transdermal vaccine delivery. J. Liposome Res., 25, 305-314.
Timmer, M., Sauvageau, J., Foster, A. J., Ryan, J., Lagutin, K., Shaw, O., Harper, J. L., Sims I. M., Stocker, B. L. (2014) Discovery of lipids from B. longum subsp. infantis using whole cell MALDI analysis, J. Org. Chem., 79, 7332-7341.
Sauvageau, J., Khan, A., Sims, I., Stocker, B., Timmer, M. (2012) Synthesis and biological activity of the lipotechoic acid anchor from Streptococcus sp. DSM 8747. ChemBioChem, 13, 2416-2424.
Sauvageau, J., Ryan, J., Lagutin, K., Sims, I., Stocker, B., Timmer, M. (2012) Isolation and structural characterisation of the major glycolipids from Lactobacillus plantarum. Carbohydr. Res., 357, 151-156.
Sauvageau, J., Sims, I.M., Hinkley, S. F., Carnachan, S. (2010). Characterisation of polysaccharides from ZESPRI GOLD kiwifruit. Carbohydr. Polym. 82, 1110–1115.
Previous work experience
September 2014— September 2018
- Synthesis and synthesis design for different carbohydrate targets
- Intellectual property protection of discoveries
- Publish research results
International experience and/or work
April, 2008 — October, 2009
Industrial Research Limited, Wellington, New Zealand
- Analysis of biomaterials using GC-MS, NMR and HPLC
- Synthesis of carbohydrate derivatives